Transfected Stable Cell Lines
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Cat. No. : RP00028 Tag : C-6His
Expressed Region : Ala19-Asp707 Expression System : Human Cell
| Cat. No. | RP00028 |
| Description | The Recombinant Human MMP-9 (C-6His) is produced in our Human Cell expression system. The amino acid region expressed is Ala19-Asp707 with a 6His tag at the C terminus. |
| Species | Human |
| Tag | C-6His |
| Mol Weight | 77.4 KDa |
| Conjugate | Unconjugated |
| Format | Liquid |
| Expressed Region | Ala19-Asp707 |
| Expression System | Human Cell |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM Hepes,10% Sucrose,150mM NaCl,0.05% Tween 80,2mM CaCl2,pH8.0. |
| Purity |
>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS. |
| Endotoxin Level | < 1 EU/µg of protein by LAL method |
| Storage | Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles. |
| Shipping | The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below. |
| Target Gene | MMP-9 |
| Background | Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. |
| Synonyms | Matrix metalloproteinase-9; 92 kDa gelatinase; 92 kDa type IV collagenase; Gelatinase B; MMP9 |
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