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Human MMP-9 ORF clone(NM_004994.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCL185376

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Product Information

Gene Information

Cat. No. CDCL185376
Product Type ORF clone
Gene Abbr MMP-9
Species Human
ORF Size 2124bp
Vector pMD18-T
Warning This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Storage store at -20°C
Target Gene MMP-9
Background Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. [provided by RefSeq, Jul 2008]
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