Recombinant Human MAPT (624-756aa, C-6His)

Name: Recombinant Human MAPT (624-756aa, C-6His)
SKU: RP00622
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : RP00622 Tag : C-6His

Expressed Region : Gln624-Gln756 Expression System : E.coli

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Product Information

Gene Information

Cat. No.	RP00622
Description	Recombinant Human MAPT (624-756aa, C-6His) is produced in our E.coli expression system. The amino acid region expressed is Gln624-Gln756 with a 6His tag at the C terminus.
Species	Human
Tag	C-6His
Mol Weight	15.37 KDa
Format	Powder
Expressed Region	Gln624-Gln756
Expression System	E.coli
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, 1mM PMSF, pH 7.4.
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Endotoxin Level	< 1 EU/µg of protein by LAL method
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Reconstitution	Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Target Gene	MAPT
Background	This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.
Synonyms	Microtubule-Associated Protein Tau; Neurofibrillary Tangle Protein; Paired Helical Filament-Tau; PHF-Tau; MAPT; MAPTL; MTBT1; TAU

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