Recombinant Human KARS (C-6His)

Name: Recombinant Human KARS (C-6His)
SKU: RP00148

Cat.No. : RP00148 Tag: C-6His

Expressed Region: Ala2-Val597 Expression System: Human Cell

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Product Details

Target Information

Cat. No.	RP00148
Description	The Recombinant Human KARS (C-6His) is produced in our Human Cell expression system. The amino acid region expressed is Ala2-Val597 with a 6His tag at the C terminus.
Species	Human
Tag	C-6His
Mol. Weight	69.1 KDa
Expressed Region	Ala2-Val597
Expression System	Human Cell
Format	Liquid
Formulation	Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, 1mM DTT, 20% Glycerol, pH 8.0.
Conjugate	Unconjugated
Endotoxin Level	< 1 EU/µg of protein by LAL method
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.

Target Gene	KARS
Background	This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region.
Synonyms	Lysine--tRNA Ligase; Lysyl-tRNA Synthetase; LysRS; KARS; KIAA0070

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