Recombinant Human KARS (C-6His)

Name: Recombinant Human KARS (C-6His)
SKU: RP00148
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : RP00148 Tag : C-6His

Expressed Region : Ala2-Val597 Expression System : Human Cell

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Product Information

Gene Information

Cat. No.	RP00148
Description	The Recombinant Human KARS (C-6His) is produced in our Human Cell expression system. The amino acid region expressed is Ala2-Val597 with a 6His tag at the C terminus.
Species	Human
Tag	C-6His
Mol Weight	69.1 KDa
Conjugate	Unconjugated
Format	Liquid
Expressed Region	Ala2-Val597
Expression System	Human Cell
Formulation	Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, 1mM DTT, 20% Glycerol, pH 8.0.
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Endotoxin Level	< 1 EU/µg of protein by LAL method
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.

Target Gene	KARS
Background	This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region.
Synonyms	Lysine--tRNA Ligase; Lysyl-tRNA Synthetase; LysRS; KARS; KIAA0070

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