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Rat Kars cDNA Clone(NM_001006967.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR001497

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Gene Information

Cat. No. CDFR001497
Description NativeORF clone of Rattus norvegicus lysyl-tRNA synthetase (Kars) as transfection-ready DNA NM_001006967.1
Product Type cDAN Clone
Gene Abbr Kars
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene KARS
Background This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008]
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