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Recombinant Human HMGB1 (C-His)

For research use only. Not intended for any clinical use.

Cat. No. :   RP00659 Tag :   C-His

Expressed Region :   Met1-Glu215 Expression System :   E. coli

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Product Information

Gene Information

Cat. No. RP00659
Description The Recombinant Human HMGB1 (C-His) is produced in our E. coli expression system. The amino acid region expressed is Met1-Glu215 with a His tag at the C terminus.
Species Human
Tag C-His
Mol Weight 32~35 kDa, on SDS-PAGE under reducing conditions.
Format Powder
Expressed Region Met1-Glu215
Expression System E. coli
Formulation Lyophilized from a 0.2 μm filtered solution in PBS, pH 7.4.
Purity > 95% as analyzed by SDS-PAGE> 95% as analyzed by HPLC
Endotoxin Level < 1 EU/μg of protein by LAL method
Storage Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Reconstitution Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Target Gene HMGB1
Background This gene encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein.
Synonyms HMGB1; HMG-1; High mobility group protein 1; HMG1; High mobility group protein B1
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