Recombinant Human GUCY2C (C-6His)

Name: Recombinant Human GUCY2C (C-6His)
SKU: RP00248
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : RP00248 Tag : C-6His

Expressed Region : Ser24-Gln430 Expression System : Human Cell

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Product Information

Gene Information

Cat. No.	RP00248
Description	The Recombinant Human GUCY2C (C-6His) is produced in our Human Cell expression system. The amino acid region expressed is Ser24-Gln430 with a 6His tag at the C terminus.
Species	Human
Tag	C-6His
Mol Weight	46.8 KDa
Conjugate	Unconjugated
Format	Powder
Expressed Region	Ser24-Gln430
Expression System	Human Cell
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Endotoxin Level	< 1 EU/µg of protein by LAL method
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Reconstitution	Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Target Gene	GUCY2C
Background	This gene encodes a transmembrane protein that functions as a receptor for endogenous peptides guanylin and uroguanylin, and the heat-stable E. coli enterotoxin. The encoded protein activates the cystic fibrosis transmembrane conductance regulator. Mutations in this gene are associated with familial diarrhea (autosomal dominant) and meconium ileus (autosomal recessive).
Synonyms	Heat-stable enterotoxin receptor; GUCY2C; STA receptor; hSTAR; Guanylyl cyclase C; GC-C; Intestinal guanylate cyclase; GUC2C; STAR

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