Humanized GUCY2C Murine Tumor Cell Line

Name: Humanized GUCY2C Murine Tumor Cell Line
SKU: CSC-RH0038M
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-RH0038M Size : >1x10⁶ frozen cells/vial

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Cell Line Information

Safety and Packaging

Gene Information

Cat. No.	CSC-RH0038M
Description	This cell line is engineered to stably express chimeric GUCY2C containing human extracellular region and mouse intracellular region. The endogenous mouse Gucy2c gene was disrupted, resulting in a non-functional transcript.
Target Gene	GUCY2C
Alias	DIAR6, GC-C, GUC2C, MECIL, MUCIL, STAR
Size	>1x10⁶ frozen cells/vial
Storage	Liquid nitrogen
Shipping	Dry ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	GUCY2C guanylate cyclase 2C (heat stable enterotoxin receptor) [ Homo sapiens ]
Gene Symbol	GUCY2C
Synonyms	STAR; DIAR6; GUC2C; MUCIL
GeneID	2984
Uni ProtID	P25092
mRNA Refseq	NM_004963.3
Protein Refseq	NP_004954.2
Chromosome Location	12p12
Function	ATP binding; GTP binding; guanylate cyclase activity; protein binding; protein kinase activity; toxin binding;
Pathway	Purine metabolism, organism-specific biosystem; Purine metabolism, conserved biosystem;
MIM	601330

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