Recombinant Human ENPP-2 (C-6His)

Name: Recombinant Human ENPP-2 (C-6His)
SKU: RP00399
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : RP00399 Tag : C-6His

Expressed Region : Ala36-Ile863 Expression System : Human Cell

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Product Information

Gene Information

Cat. No.	RP00399
Description	The Recombinant Human ENPP-2 (C-6His) is produced in our Human Cell expression system. The amino acid region expressed is Ala36-Ile863 with a 6His tag at the C terminus.
Species	Human
Tag	C-6His
Mol Weight	96 KDa
Conjugate	Unconjugated
Format	Powder
Expressed Region	Ala36-Ile863
Expression System	Human Cell
Formulation	Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Endotoxin Level	< 1 EU/µg of protein by LAL method
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Reconstitution	Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Target Gene	ENPP2
Background	The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified.
Synonyms	ATX; ATXFLJ26803; ATX-X; Autotaxin; autotaxin-t; EC 3.1.4.39; ectonucleotide pyrophosphatase/phosphodiesterase 2; E-NPP 2; ENPP2; LysoPLD; NPP2; PD-IALPHA; PDNP2; PDNP2NPP2

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