Recombinant Human DLK-1 (C-6His)

Name: Recombinant Human DLK-1 (C-6His)
SKU: RP00386
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : RP00386 Tag : C-6His

Expressed Region : Ala24-Pro297(Ser260Asn) Expression System : Human Cell

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Product Information

Gene Information

Cat. No.	RP00386
Description	The Recombinant Human DLK-1 (C-6His) is produced in our Human Cell expression system. The amino acid region expressed is Ala24-Pro297(Ser260Asn) with a 6His tag at the C terminus.
Species	Human
Tag	C-6His
Mol Weight	30.15 KDa
Conjugate	Unconjugated
Format	Powder
Expressed Region	Ala24-Pro297(Ser260Asn)
Expression System	Human Cell
Formulation	Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Endotoxin Level	< 1 EU/µg of protein by LAL method
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Reconstitution	Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Target Gene	DLK1
Background	This gene encodes a transmembrane protein that contains multiple epidermal growth factor repeats that functions as a regulator of cell growth. The encoded protein is involved in the differentiation of several cell types including adipocytes. This gene is located in a region of chromosome 14 frequently showing unparental disomy, and is imprinted and expressed from the paternal allele. A single nucleotide variant in this gene is associated with child and adolescent obesity and shows polar overdominance, where heterozygotes carrying an active paternal allele express the phenotype, while mutant homozygotes are normal.
Synonyms	Protein Delta Homolog 1; DLK-1; pG2; DLK1; DLK

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