Mouse DLK1 ORF clone(NM_010052.5)

Name: Mouse DLK1 ORF clone(NM_010052.5)
SKU: CDCH385589
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCH385589

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Product Information

Gene Information

Cat. No.	CDCH385589
Product Type	ORF clone
Gene Abbr	DLK1
Species	Mouse
Host Cell	Bacterial
Source	Bacterial
ORF Size	4339bp
Size	1ug
Format	Clear Liquid
Vector	pORF
Buffer	10mM Tris-HCI, 1mM EDTA, pH8.0
Warning	pORF-mDlk1 ORF Vector is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information.
Storage	1 year when stored at -20°C or lower in a non-frost free freezer.

Target Gene

DLK1

Background

This gene encodes a transmembrane protein that contains multiple epidermal growth factor repeats that functions as a regulator of cell growth. The encoded protein is involved in the differentiation of several cell types including adipocytes. This gene is located in a region of chromosome 14 frequently showing unparental disomy, and is imprinted and expressed from the paternal allele. A single nucleotide variant in this gene is associated with child and adolescent obesity and shows polar overdominance, where heterozygotes carrying an active paternal allele express the phenotype, while mutant homozygotes are normal. [provided by RefSeq, Nov 2015]

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