Recombinant Human CLEC12A (N-Fc)

Name: Recombinant Human CLEC12A (N-Fc)
SKU: RP00121
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : RP00121 Tag : N-Fc

Expressed Region : His65-Ala265 Expression System : Human Cell

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Product Information

Gene Information

Cat. No.	RP00121
Description	The Recombinant Human CLEC12A (N-Fc) is produced in our Human Cell expression system. The amino acid region expressed is His65-Ala265 with a Fc tag at the N terminus.
Species	Human
Tag	N-Fc
Mol Weight	49.5 KDa
Format	Powder
Expressed Region	His65-Ala265
Expression System	Human Cell
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Endotoxin Level	< 1 EU/µg of protein by LAL method
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Reconstitution	Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Target Gene	CLEC12A
Background	This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signaling, glycoprotein turnover, and roles in inflammation and immune response. The protein encoded by this gene is a negative regulator of granulocyte and monocyte function. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. This gene is closely linked to other CTL/CTLD superfamily members in the natural killer gene complex region on chromosome 12p13.
Synonyms	C-type lectin domain family 12 member A; CLEC12A; C-type lectin-like molecule 1; Dendritic cell-associated lectin 2; CD371; CLL1; DCAL2; MICL

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