Recombinant Cynomolgus IL-13 (C-6His)

Name: Recombinant Cynomolgus IL-13 (C-6His)
SKU: RP00116
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : RP00116 Tag : C-6His

Expressed Region : Ser19-Asn132 Expression System : Human Cell

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Product Information

Gene Information

Cat. No.	RP00116
Description	The Recombinant Cynomolgus IL-13 (C-6His) is produced in our Human Cell expression system. The amino acid region expressed is Ser19-Asn132 with a 6His tag at the C terminus.
Species	Cynomolgus
Tag	C-6His
Mol Weight	13.3 KDa
Format	Powder
Expressed Region	Ser19-Asn132
Expression System	Human Cell
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Endotoxin Level	< 1 EU/µg of protein by LAL method
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Reconstitution	Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Target Gene	IL-13
Background	This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4.
Synonyms	Interleukin-13; IL-13; T-Cell Activation Protein P600; Il13; Il-13

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