Humanized C5 Murine Tumor Cell Line

Name: Humanized C5 Murine Tumor Cell Line
SKU: CSC-RH0074M
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-RH0074M Size : >1x10⁶ frozen cells/vial

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Cell Line Information

Safety and Packaging

Gene Information

Cat. No.	CSC-RH0074M
Description	These transgenic cells carry humanized C5 and form solid tumors in vivo. The endogenous mouse C5 gene was replaced by human C5 gene.
Target Gene	C5
Alias	C5Da, C5b, CPAMD4, ECLZB
Size	>1x10⁶ frozen cells/vial
Storage	Liquid nitrogen
Shipping	Dry ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	C5 complement component 5 [ Homo sapiens ]
Gene Symbol	C5
Synonyms	C5; complement component 5; complement C5; CPAMD4; anaphylatoxin C5a analog; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4; FLJ17816; FLJ17822; MGC142298;
GeneID	727
Uni ProtID	P01031
mRNA Refseq	BC113740
Chromosome Location	9q33-q34
Function	C5a anaphylatoxin chemotactic receptor binding; chemokine activity; endopeptidase inhibitor activity; receptor binding;
Pathway	Activation of C3 and C5, organism-specific biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Complement Activation, Classical Pathway, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; Complement cascade, organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem;
MIM	120900

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