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Human TNFRSF8 mRNA

For research use only. Not intended for any clinical use.
Cat.No.
PMRN-0240
Description
The TNFRSF8 mRNA encodes the human TNF receptor superfamily member 8 (TNFRSF8) protein, a member of the TNF receptor superfamily. TNFRSF8 is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity.
Alias
CD30, D1S166E, Ki-1
Features
• mRNA synthesized on error free sequence verified plasmid DNA template
• 100% replacement of UTP with modified nucleotides 5-Methoxy-UTP
• Cap 1 Capping and poly-A tailed incorporated
• Degrades the DNA template after RNA synthesis with DNase
Sequence
MRVLLAALGL LFLGALRAFP QDRPFEDTCH GNPSHYYDKA VRRCCYRCPM GLFPTQQCPQ RPTDCRKQCE PDYYLDEADR CTACVTCSRD DLVEKTPCAW NSSRVCECRP GMFCSTSAVN SCARCFFHSV CPAGMIVKFP GTAQKNTVCE PASPGVSPAC ASPENCKEPS SGTIPQAKPT PVSPATSSAS TMPVRGGTRL AQEAASKLTR APDSPSSVGR PSSDPGLSPT QPCPEGSGDC RKQCEPDYYL DEAGRCTACV SCSRDDLVEK TPCAWNSSRT CECRPGMICA TSATNSCARC VPYPICAAET VTKPQDMAEK DTTFEAPPLG TQPDCNPTPE NGEAPASTSP TQSLLVDSQA SKTLPIPTSA PVALSSTGKP VLDAGPVLFW VILVLVVVVG SSAFLLCHRR ACRKRIRQKL HLCYPVQTSQ PKLELVDSRP RRSSTQLRSG ASVTEPVAEE RGLMSQPLME TCHSVGAAYL ESLPLQDASP AGGPSSPRDL PEPRVSTEHT NNKIEKIYIM KADTVIVGTV KAELPEGRGL AGPAEPELEE ELEADHTPHY PEQETEPPLG SCSDVMLSVE EEGKEDPLPT AASGK
Species
Homo sapiens (Human)
Storage
Store at or below -70°C. Avoid repeated freeze/thaw cycles. Aliquot if necessary using RNase-free equipment, reagents, pipet tips, tubes, and containers.

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Q & A

Customer Reviews

Customer Q&As
What is TNFRSF8?

A: TNFRSF8 (TNF receptor superfamily member 8) is a protein-coding gene. Diseases associated with TNFRSF8 include peripheral T-cell lymphoma and reticulosarcoma.

Is TNFRSF8 homologous to human TNFRSF8?

A: Directly homologous to human TNFSF8 (TNF superfamily member 8).

What is the TNF gene?

A: TNF genes are -immediate early genes that are rapidly transcribed in a variety of cell types after exposure to a wide range of pathogens as well as inflammatory and stress signals.

What is the function of TNFRS?

A: Tumor necrosis factor receptors (TNFRs) are a family of structurally similar membrane proteins that act as communication pathways that activate cell death pathways or induce the expression of genes involved in cell differentiation and survival. These receptors act in many organ systems and are prominent in the immune system.

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Customer Reviews
Time saving

When doing tumor necrosis knockout experiments, it is very easy to use and the tumor cells backfill the experimental data, easy to detect and good to use.

United States

01/27/2022

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