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Human TNFRSF4 mRNA

For research use only. Not intended for any clinical use.
Cat.No.
PMRN-0239
Description
The TNFRSF4 mRNA encodes the human TNF receptor superfamily member 4 (TNFRSF4) protein, a member of the TNF receptor superfamily. TNFRSF4 has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5.
Alias
ACT35, CD134, IMD16, OX40, TXGP1L
Features
• mRNA synthesized on error free sequence verified plasmid DNA template
• 100% replacement of UTP with modified nucleotides 5-Methoxy-UTP
• Cap 1 Capping and poly-A tailed incorporated
• Degrades the DNA template after RNA synthesis with DNase
Sequence
MCVGARRLGR GPCAALLLLG LGLSTVTGLH CVGDTYPSND RCCHECRPGN GMVSRCSRSQ NTVCRPCGPG FYNDVVSSKP CKPCTWCNLR SGSERKQLCT ATQDTVCRCR AGTQPLDSYK PGVDCAPCPP GHFSPGDNQA CKPWTNCTLA GKHTLQPASN SSDAICEDRD PPATQPQETQ GPPARPITVQ PTEAWPRTSQ GPSTRPVEVP GGRAVAAILG LGLVLGLLGP LAILLALYLL RRDQRLPPDA HKPPGGGSFR TPIQEEQADA HSTLAKI
Species
Homo sapiens (Human)
Storage
Store at or below -70°C. Avoid repeated freeze/thaw cycles. Aliquot if necessary using RNase-free equipment, reagents, pipet tips, tubes, and containers.

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Q & A

Customer Reviews

Customer Q&As
What is Human TNFRSF4 mRNA?

A: Human TNFRSF4 mRNA is the messenger RNA molecule for the human TNFRSF4 gene.TNFRSF4 is a gene that encodes the T-cell co-stimulatory molecule CD134.

What is the function of the TNFRSF4 gene?

A: The CD134 encoded by the TNFRSF4 gene is a receptor protein on the cell membrane that plays an important role in T-cell activation and proliferation.Binding of CD134 to its ligand, CD134L, promotes T-cell proliferation, differentiation, and production of cytokines, thereby regulating the immune response.

What is the role of TNFRSF4 mRNA in the immune response?

A: CD134, encoded by TNFRSF4 mRNA, plays an important role in the immune response.Binding of CD134 to its ligand, CD134L, activates T cells and promotes T cell proliferation, differentiation, and cytokine production, thereby enhancing the immune response.

What are the implications of TNFRSF4 mRNA studies for understanding immune regulation?

A: The study of TNFRSF4 mRNA can help us better understand the mechanism of immune regulation.TNFRSF4, as a T-cell co-stimulatory molecule, plays an important role in immune response.Understanding its regulatory mechanism can help to reveal the molecular mechanism of immune regulation, and provide a theoretical basis for immune diseases and tumor immunotherapy, etc.The study of TNFRSF4 mRNA can help us better understand the mechanism of immune regulation.

What are the implications of TNFRSF4 mRNA research for new drug development?

A: The study of TNFRSF4 as an immunomodulatory molecule and its mRNA provides potential targets for new drug development. By interfering with the expression or function of TNFRSF4, the immune response can be regulated, providing new therapeutic strategies for the treatment of immune-related diseases.

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Customer Reviews
Worked Very Well

When I got this reagent, I thought the experimental process would b uneventful. But it far exceeded my expectations accurately and efficiently expressed TNFRSF4 mRNA, loved it and got the expected results, will repurchase.

United States

01/27/2022

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