Human TGFB2 mRNA

Name: Human TGFB2 mRNA
SKU: PMRN-0178

For research use only. Not intended for any clinical use.

Cat.No.

PMRN-0178

Description

The TGFB2 mRNA encodes the human transforming growth factor beta 2 (TGFB2) protein, a secreted ligand of the TGF-beta superfamily. TGFB2 has suppressive effects on interleukin-2 dependent T-cell growth.

Alias

LDS4; G-TSF; TGF-beta2

Features

• mRNA synthesized on error free sequence verified plasmid DNA template
• 100% replacement of UTP with modified nucleotides 5-Methoxy-UTP
• Cap 1 Capping and poly-A tailed incorporated
• Degrades the DNA template after RNA synthesis with DNase

Sequence

MHYCVLSAFL ILHLVTVALS LSTCSTLDMD QFMRKRIEAI RGQILSKLKL TSPPEDYPEP EEVPPEVISI YNSTRDLLQE KASRRAAACE RERSDEEYYA KEVYKIDMPP FFPSENAIPP TFYRPYFRIV RFDVSAMEKN ASNLVKAEFR VFRLQNPKAR VPEQRIELYQ ILKSKDLTSP TQRYIDSKVV KTRAEGEWLS FDVTDAVHEW LHHKDRNLGF KISLHCPCCT FVPSNNYIIP NKSEELEARF AGIDGTSTYT SGDQKTIKST RKKNSGKTPH LLLMLLPSYR LESQQTNRRK KRALDAAYCF RNVQDNCCLR PLYIDFKRDL GWKWIHEPKG YNANFCAGAC PYLWSSDTQH SRVLSLYNTI NPEASASPCC VSQDLEPLTI LYYIGKTPKI EQLSNMIVKS CKCS

Species

Homo sapiens (Human)

Storage

Store at or below -70°C. Avoid repeated freeze/thaw cycles. Aliquot if necessary using RNase-free equipment, reagents, pipet tips, tubes, and containers.

Publications

Q & A

Customer Reviews

Customer Q&As

What is Human TGFB2 mRNA?

A: Human TGFB2 mRNA is the messenger RNA of the human TGFB2 gene. TGFB2 (transforming growth factor beta 2) is a multifunctional cytokine that participates in processes such as cell proliferation, differentiation, migration, and apoptosis, playing important physiological and pathological roles in the human body.

What is the role of Human TGFB2 mRNA in the human body?

A: The function of Human TGFB2 mRNA is to encode the TGFB2 protein. TGFB2 can participate in various biological processes in the human body, including embryonic development, immune regulation, hematopoiesis, and tumorigenesis. It can regulate cell proliferation, differentiation, apoptosis, and migration, and plays an important role in maintaining in vivo balance and tissue repair.

In which cells is Human TGFB2 mRNA expressed?

A: Human TGFB2 mRNA is expressed in various cells, including bone marrow-derived cells, endothelial cells, epithelial cells, and tumor cells. Its expression level can be induced or inhibited by various factors such as growth factors, cytokines, and chemicals.

How is the expression of Human TGFB2 mRNA regulated?

A: The expression of Human TGFB2 mRNA is finely regulated. The processes of gene transcription and post-transcriptional modification are jointly involved in the regulation of its expression. Some transcription factors and signal transduction pathways can affect the transcription of TGFB2 gene. Meanwhile, some translation regulatory factors can also affect their translation efficiency and stability.

What diseases are associated with Human TGFB2 mRNA?

A: Research has shown that Human TGFB2 mRNA is associated with some chronic inflammatory diseases, autoimmune diseases, and tumors. In these diseases, the expression level of TGFB2 may change, thereby affecting the progression and prognosis of the disease.

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