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Human PAX4 mRNA

For research use only. Not intended for any clinical use.
Cat.No.
PMRN-0280
Description
The PAX4 mRNA encodes the human paired box 4 (PAX4) protein, a member of the paired box (PAX) family. PAX4 is involved in pancreatic islet development and mouse studies have demonstrated a role for this gene in differentiation of insulin-producing beta cells.
Alias
KPD, MODY9
Features
• mRNA synthesized on error free sequence verified plasmid DNA template
• 100% replacement of UTP with modified nucleotides 5-Methoxy-UTP
• Cap 1 Capping and poly-A tailed incorporated
• Degrades the DNA template after RNA synthesis with DNase
Sequence
MHQDGISSMN QLGGLFVNGR PLPLDTRQQI VRLAVSGMRP CDISRILKVS NGCVSKILGR YYRTGVLEPK GIGGSKPRLA TPPVVARIAQ LKGECPALFA WEIQRQLCAE GLCTQDKTPS VSSINRVLRA LQEDQGLPCT RLRSPAVLAP AVLTPHSGSE TPRGTHPGTG HRNRTIFSPS QAEALEKEFQ RGQYPDSVAR GKLATATSLP EDTVRVWFSN RRAKWRRQEK LKWEMQLPGA SQGLTVPRVA PGIISAQQSP GSVPTAALPA LEPLGPSCYQ LCWATAPERC LSDTPPKACL KPCWDCGSFL LPVIAPSCVD VAWPCLDASL AHHLIGGAGK ATPTHFSHWP
Species
Homo sapiens (Human)
Storage
Store at or below -70°C. Avoid repeated freeze/thaw cycles. Aliquot if necessary using RNase-free equipment, reagents, pipet tips, tubes, and containers.

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Q & A

Customer Reviews

Customer Q&As
Which organ of the body is associated with the development of the PAX4 gene?

A: The PAX4 gene is involved in the development of pancreatic islets, and mouse studies have shown that this gene plays a role in the differentiation of insulin-secreting β-cells.

What is the function of the human PAX4 gene?

A: This gene plays a key role in fetal development and cancer growth.

What role might PAX4 mRNA play in human tumor diseases in the future?

A: According to the results in the literature, overexpression of PAX4 mRNA was able to induce DNA methylation inhibited PAX4 gene expression in human melanoma. These results suggest that PAX4 has potent tumor suppressive effects.

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Customer Reviews
Easy to Use

I used the product PAX4 mRNA with my lab brother, he did tumor related experiments and I did islet related experiments and found that we both got the expected results and the instructions were very clear and novice friendly.

United States

03/25/2022

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