Transfected Stable Cell Lines
Reliable | High-Performance | Wide Rage
Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : PMRN-0280
| Cat. No. | PMRN-0280 |
| Description | The PAX4 mRNA encodes the human paired box 4 (PAX4) protein, a member of the paired box (PAX) family. PAX4 is involved in pancreatic islet development and mouse studies have demonstrated a role for this gene in differentiation of insulin-producing beta cells. |
| Gene Type | Other |
| RNA Type | mRNA |
| Gene Name | PAX4 |
| Species | Homo sapiens (Human) |
| Alias | KPD, MODY9 |
| Features |
• mRNA synthesized on error free sequence verified plasmid DNA template • 100% replacement of UTP with modified nucleotides 5-Methoxy-UTP • Cap 1 Capping and poly-A tailed incorporated • Degrades the DNA template after RNA synthesis with DNase |
| Sequence | MHQDGISSMN QLGGLFVNGR PLPLDTRQQI VRLAVSGMRP CDISRILKVS NGCVSKILGR YYRTGVLEPK GIGGSKPRLA TPPVVARIAQ LKGECPALFA WEIQRQLCAE GLCTQDKTPS VSSINRVLRA LQEDQGLPCT RLRSPAVLAP AVLTPHSGSE TPRGTHPGTG HRNRTIFSPS QAEALEKEFQ RGQYPDSVAR GKLATATSLP EDTVRVWFSN RRAKWRRQEK LKWEMQLPGA SQGLTVPRVA PGIISAQQSP GSVPTAALPA LEPLGPSCYQ LCWATAPERC LSDTPPKACL KPCWDCGSFL LPVIAPSCVD VAWPCLDASL AHHLIGGAGK ATPTHFSHWP |
| Storage | Store at or below -70°C. Avoid repeated freeze/thaw cycles. Aliquot if necessary using RNase-free equipment, reagents, pipet tips, tubes, and containers. |
A: The PAX4 gene is involved in the development of pancreatic islets, and mouse studies have shown that this gene plays a role in the differentiation of insulin-secreting β-cells.
A: This gene plays a key role in fetal development and cancer growth.
A: According to the results in the literature, overexpression of PAX4 mRNA was able to induce DNA methylation inhibited PAX4 gene expression in human melanoma. These results suggest that PAX4 has potent tumor suppressive effects.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
I used the product PAX4 mRNA with my lab brother, he did tumor related experiments and I did islet related experiments and found that we both got the expected results and the instructions were very clear and novice friendly.
Write a review of your use of Biogene products and services in your research. Your review can help your fellow researchers make informed purchasing decisions.