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Human NEUROG2 mRNA

For research use only. Not intended for any clinical use.
Cat.No.
PMRN-0046
Description
NEUROG2 mRNA encodes a neural-specific basic helix-loop-helix (bHLH) transcription factor that can specify a neuronal fate on ectodermal cells. NEUROG2 plays a role in the differentiation and survival of midbrain dopaminergic neurons.
Alias
NGN2; Atoh4; ngn-2; Math4A; bHLHa8
Features
• mRNA synthesized on error free sequence verified plasmid DNA template
• 100% replacement of UTP with modified nucleotides 5-Methoxy-UTP
• Cap 1 Capping and poly-A tailed incorporated
• Degrades the DNA template after RNA synthesis with DNase
Sequence
MFVKSETLEL KEEEDVLVLL GSASPALAAL TPLSSSADEE EEEEPGASGG ARRQRGAEAG QGARGGVAAG AEGCRPARLL GLVHDCKRRP SRARAVSRGA KTAETVQRIK KTRRLKANNR ERNRMHNLNA ALDALREVLP TFPEDAKLTK IETLRFAHNY IWALTETLRL ADHCGGGGGG LPGALFSEAV LLSPGGASAA LSSSGDSPSP ASTWSCTNSP APSSSVSSNS TSPYSCTLSP ASPAGSDMDY WQPPPPDKHR YAPHLPIARD CI
Species
Homo sapiens (Human)
Storage
Store at or below -70°C. Avoid repeated freeze/thaw cycles. Aliquot if necessary using RNase-free equipment, reagents, pipet tips, tubes, and containers.

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Q & A

Customer Reviews

Customer Q&As
What is Human NEUROG2 mRNA?

A: NEUROG2 mRNA is a messenger RNA molecule of human genes that encodes the NEUROG2 protein.

What role does NEUROG2 protein play in the human body?

A: NEUROG2 protein is a transcription factor that plays a crucial role in embryonic development, especially in the formation and differentiation of the nervous system.

What is the expression pattern of NEUROG2 mRNA?

A: The expression of NEUROG2 mRNA is mainly concentrated in the development of the central nervous system, especially in the differentiation of neural Precursor cell and neuronal generation.

In which tissues is NEUROG2 mRNA expressed?

A: NEUROG2 mRNA is mainly expressed in the central nervous system, including the brain, spinal cord and neural Precursor cell.

Are mutations in NEUROG2 mRNA associated with certain diseases?

A: Yes, mutations in NEUROG2 mRNA have been found to be associated with some neurological related diseases, such as epilepsy and neurodevelopmental disorders.

What is the function of NEUROG2 mRNA?

A: NEUROG2, a protein encoded by NEUROG2 mRNA, plays a key role in the development of the nervous system, promoting the differentiation of neural Precursor cell into neurons, and participating in the directional migration of neurons and axon elongation.

What is the application value of NEUROG2 mRNA research?

A: The study of NEUROG2 mRNA can help us better understand the development and function of the nervous system, and has important application value in the treatment of Nervous system disease and Regenerative medicine.

What signaling pathways regulate the expression of NEUROG2 mRNA?

A: The expression of NEUROG2 mRNA is regulated by various signaling pathways, including Notch signaling pathway, Wnt signaling pathway, and transcription factors.

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Customer Reviews
Worked Very Well

When I got this reagent, I thought the experimental process would go smoothly. But it far exceeded my expectations by accurately and efficiently expressing NEUROG2 mRNA, liking it and achieving the expected results, and will be re obtained.

France

04/11/2023

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