Human NEUROD2 mRNA

Name: Human NEUROD2 mRNA
SKU: PMRN-0045

For research use only. Not intended for any clinical use.

Cat.No.

PMRN-0045

Description

The NEUROD2 mRNA encodes the human neuronal differentiation 2 (NEUROD2) protein, a member of the neuroD family of neurogenic basic helix-loop-helix (bHLH) proteins. Human NEUROD2 can induce neurogenic differentiation in non-neuronal cells in Xenopus embryos, and is thought to play a role in the determination and maintenance of neuronal cell fates.

Alias

NDRF; EIEE72; bHLHa1

Features

• mRNA synthesized on error free sequence verified plasmid DNA template
• 100% replacement of UTP with modified nucleotides 5-Methoxy-UTP
• Cap 1 Capping and poly-A tailed incorporated
• Degrades the DNA template after RNA synthesis with DNase

Sequence

MLTRLFSEPG LLSDVPKFAS WGDGEDDEPR SDKGDAPPPP PPAPGPGAPG PARAAKPVPL RGEEGTEATL AEVKEEGELG GEEEEEEEEE EGLDEAEGER PKKRGPKKRK MTKARLERSK LRRQKANARE RNRMHDLNAA LDNLRKVVPC YSKTQKLSKI ETLRLAKNYI WALSEILRSG KRPDLVSYVQ TLCKGLSQPT TNLVAGCLQL NSRNFLTEQG ADGAGRFHGS GGPFAMHPYP YPCSRLAGAQ CQAAGGLGGG AAHALRTHGY CAAYETLYAA AGGGGASPDY NSSEYEGPLS PPLCLNGNFS LKQDSSPDHE KSYHYSMHYS ALPGSRPTGH GLVFGSSAVR GGVHSENLLS YDMHLHHDRG PMYEELNAFF HN

Species

Homo sapiens (Human)

Storage

Store at or below -70°C. Avoid repeated freeze/thaw cycles. Aliquot if necessary using RNase-free equipment, reagents, pipet tips, tubes, and containers.

Publications

Q & A

Customer Reviews

Customer Q&As

What is Human NEUROD2 mRNA?

A: Human NEUROD2 mRNA, a messenger RNA molecule of the human neurodevelopmental transcription factor 2 gene, encodes the NEUROD2 protein, an important regulator in neuronal development and maturation.

In which tissues is the NEUROD2 gene expressed?

A: The NEUROD2 gene is mainly expressed in the brain, including cortical, hippocampal, thalamic and cerebellar regions.

In which physiological processes does NEUROD2 mRNA play a role?

A: NEUROD2 mRNA plays an important role in physiological processes such as neuronal development and maturation, synapse formation and functional maintenance.

What diseases can be caused by abnormal expression of NEUROD2 mRNA?

A: Aberrant expression of NEUROD2 mRNA may be associated with neurological disorders such as epilepsy, autism, Parkinson's disease and Alzheimer's disease.

What are the post-translational modifications of NEUROD2 mRNA?

A: NEUROD2 proteins may undergo post-translational modifications, such as phosphorylation, methylation, and ubiquitination, which help regulate the function and stability of NEUROD2 proteins.

What are the structural features of NEUROD2 mRNA?

A: NEUROD2 mRNA consists of a 5' end cap, a 5' untranslated region, a coding region, a 3' untranslated region and a 3' end polyadenylate tail with a length of about 1.8 kb.

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