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Human MITF mRNA

For research use only. Not intended for any clinical use.
Cat.No.
PMRN-0050
Description
The MITF mRNA encodes the human melanocyte inducing transcription factor (MITF) protein, a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. MITF could regulate melanocyte development and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes.
Alias
MI; WS2; CMM8; WS2A; COMMAD; bHLHe32
Features
• mRNA synthesized on error free sequence verified plasmid DNA template
• 100% replacement of UTP with modified nucleotides 5-Methoxy-UTP
• Cap 1 Capping and poly-A tailed incorporated
• Degrades the DNA template after RNA synthesis with DNase
Sequence
MQSESGIVPD FEVGEEFHEE PKTYYELKSQ PLKSSSSAEH PGASKPPISS SSMTSRILLR QQLMREQMQE QERREQQQKL QAAQFMQQRV PVSQTPAINV SVPTTLPSAT QVPMEVLKVQ THLENPTKYH IQQAQRQQVK QYLSTTLANK HANQVLSLPC PNQPGDHVMP PVPGSSAPNS PMAMLTLNSN CEKEGFYKFE EQNRAESECP GMNTHSRASC MQMDDVIDDI ISLESSYNEE ILGLMDPALQ MANTLPVSGN LIDLYGNQGL PPPGLTISNS CPANLPNIKR ELTACIFPTE SEARALAKER QKKDNHNLIE RRRRFNINDR IKELGTLIPK SNDPDMRWNK GTILKASVDY IRKLQREQQR AKELENRQKK LEHANRHLLL RIQELEMQAR AHGLSLIPST GLCSPDLVNR IIKQEPVLEN CSQDLLQHHA DLTCTTTLDL TDGTITFNNN LGTGTEANQA YSVPTKMGSK LEDILMDDTL SPVGVTDPLL SSVSPGASKT SSRRSSMSME ETEHTC
Species
Homo sapiens (Human)
Storage
Store at or below -70°C. Avoid repeated freeze/thaw cycles. Aliquot if necessary using RNase-free equipment, reagents, pipet tips, tubes, and containers.

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Q & A

Customer Reviews

Customer Q&As
What is Human MITF mRNA?

A: Human MITF mRNA refers to the messenger RNA molecule of the human MelanogenesisAssociatedTranscriptionFactor (MITF) gene.MITF is a transcription factor that plays an important role in regulating melanocyte development and function.

In which tissues is MITF mRNA expressed?

A: MITF mRNA is mainly expressed in tissues such as skin, eyes, hair follicles and retina. MITFmRNA in these tissues is involved in the regulation of melanocyte formation and function, and is essential for the normal development and function of the skin and visual system.

What is the function of MITF mRNA?

A: MITF mRNA encodes the protein MITF is a transcription factor that binds to specific DNA sequences in the nucleus and regulates the transcription process of other genes.MITF is particularly important in melanocytes, where it is involved in the regulation of key processes such as melanin synthesis, cell proliferation and differentiation.

What is the role of MITF mRNA in cancer?

A: MITF mRNA also plays an important role in certain cancers. For example, MITFmRNA is highly expressed in melanoma, which is closely related to the occurrence and development of melanoma. In addition, MITFmRNA may also be involved in the regulation of cell proliferation, metastasis and drug resistance in some other cancers.

What is the translation product of MITF mRNA?

A: The translation product of MITF mRNA is the MITF protein, which is a transcription factor.The MITF protein regulates the transcription process of other genes by binding to specific DNA sequences, thereby affecting cellular functions and properties.

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Customer Reviews
Saving Enormous Amounts of Material and Time

This MITF mRNA will save material, cost and time for mice in experiments. It also reduces the risk of handling errors and contamination.

United States

08/15/2021

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