Human LY6G6D Stable Cell Line - HEK293T

Name: Human LY6G6D Stable Cell Line - HEK293T
SKU: CSC-RO0849
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-RO0849

Host Cell : HEK293T Size : >1x10⁶ frozen cells/vial

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Cell Line Information

Cell Culture Information

Safety and Packaging

Gene Information

Cat. No.	CSC-RO0849
Description	This cell line is engineered to stably overexpress human LY6G6D.
Target Gene	LY6G6D
Gene Species	Homo sapiens (Human)
Host Cell	HEK293T
Host Cell Species	Homo sapiens (Human)
Applications	1. Studying the interactions between immune cells and cancer cells 2. Studying the mechanisms of resistance to immune checkpoint blockade 3. High-throughput screening 4. Drug target validation
Size	>1x10⁶ frozen cells/vial
Stability	Validated for at least 10 passages
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid nitrogen
Shipping	Dry ice

Revival	Rapidly thaw cells in a 37°C water bath. Transfer contents into a tube containing pre-warmed media. Centrifuge cells and seed into a 25 cm2 flask containing pre-warmed media.
Growth Properties	Cells are cultured as a monolayer at 37°C in a humidified atmosphere with 5% CO₂. Split at 80-90% confluence, approximately 1:3-1:6.

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	LY6G6D lymphocyte antigen 6 complex, locus G6D [ Homo sapiens ]
Gene Symbol	LY6G6D
Synonyms	G6D; NG25; LY6-D; MEGT1; C6orf23
Gene Description	lymphocyte antigen 6 complex, locus G6D
Gene ID	58530
Uni Prot ID	O95868
m RNA Refseq	NM_021246.2
Protein Refseq	NP_067069.2
Chromosome Location	6p21.3
MIM	606038

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Q & A

Customer Reviews

Customer Q&As

What is the primary function of the LY6G6D gene, and how does it relate to the Human LY6G6D Stable Cell Line - HEK293T?

A: The LY6G6D gene encodes a protein that is part of the LY6 family, which is known for its role in immune response and cell adhesion. In the context of the Human LY6G6D Stable Cell Line - HEK293T, this cell line is engineered to express the LY6G6D gene, which can be used to study the function of this gene in various cellular processes, including immune responses and cell signaling pathways.

How does the Human LY6G6D Stable Cell Line - HEK293T differ from other HEK293T cell lines in terms of genetic stability?

A: The Human LY6G6D Stable Cell Line - HEK293T is genetically modified to stably express the LY6G6D gene. This genetic stability ensures that the cells consistently express the gene of interest, which is crucial for long-term experiments and studies. In contrast, non-stable cell lines may lose the introduced gene over time due to genetic instability, leading to inconsistent results.

How does the Human LY6G6D Stable Cell Line - HEK293T contribute to the understanding of LY6G6D's role in immune cell differentiation?

A: By providing a controlled environment where LY6G6D is stably expressed, researchers can investigate its role in immune cell differentiation and function. This cell line can be used to study the effects of LY6G6D on the development and maturation of immune cells, which could lead to insights into immune system regulation.

How does the Human LY6G6D Stable Cell Line - HEK293T facilitate the study of LY6G6D's role in cancer?

A: The cell line can be used to investigate the role of LY6G6D in cancer progression, metastasis, and response to treatment. By comparing the behavior of LY6G6D-expressing cells with non-expressing cells, researchers can identify potential cancer therapeutic targets related to LY6G6D.

How does the Human LY6G6D Stable Cell Line - HEK293T aid in the development of gene therapy strategies?

A: The cell line can serve as a model system for testing gene therapy vectors designed to target LY6G6D. This can help in the development of strategies to modulate LY6G6D expression for therapeutic purposes, such as in the treatment of diseases where LY6G6D dysregulation is implicated.

What are the potential applications of the Human LY6G6D Stable Cell Line - HEK293T in drug discovery and development?

A: The Human LY6G6D Stable Cell Line - HEK293T can be used to screen for compounds that modulate the expression or function of LY6G6D. This can help in the identification of potential therapeutic agents targeting diseases where LY6G6D plays a role, such as certain immune disorders or cancers.

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