Transfected Stable Cell Lines
Reliable | High-Performance | Wide Rage
Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : PMRN-0042
| Cat. No. | PMRN-0042 |
| Description | The LMX1A mRNA encodes the human LIM homeobox transcription factor 1 alpha (LMX1A) protein, a homeodomain and LIM-domain containing protein. LMX1A is a transcription factor that acts as a positive regulator of insulin gene transcription. It also plays a role in the development of dopamine producing neurons during embryogenesis. |
| Gene Type | Other |
| RNA Type | mRNA |
| Gene Name | LMX1A |
| Species | Homo sapiens (Human) |
| Alias | LMX1; DFNA7; LMX1.1 |
| Features |
• mRNA synthesized on error free sequence verified plasmid DNA template • 100% replacement of UTP with modified nucleotides 5-Methoxy-UTP • Cap 1 Capping and poly-A tailed incorporated • Degrades the DNA template after RNA synthesis with DNase |
| Sequence | MLDGLKMEEN FQSAIDTSAS FSSLLGRAVS PKSVCEGCQR VILDRFLLRL NDSFWHEQCV QCASCKEPLE TTCFYRDKKL YCKYDYEKLF AVKCGGCFEA IAPNEFVMRA QKSVYHLSCF CCCVCERQLQ KGDEFVLKEG QLLCKGDYEK ERELLSLVSP AASDSGKSDD EESLCKSAHG AGKGTAEEGK DHKRPKRPRT ILTTQQRRAF KASFEVSSKP CRKVRETLAA ETGLSVRVVQ VWFQNQRAKM KKLARRQQQQ QQDQQNTQRL SSAQTNGGGS AGMEGIMNPY TALPTPQQLL AIEQSVYSSD PFRQGLTPPQ MPGDHMHPYG AEPLFHDLDS DDTSLSNLGD CFLATSEAGP LQSRVGNPID HLYSMQNSYF TS |
| Storage | Store at or below -70°C. Avoid repeated freeze/thaw cycles. Aliquot if necessary using RNase-free equipment, reagents, pipet tips, tubes, and containers. |
A: LMX1A mRNA encodes human LIM cis-transcription factor 1α (LMX1A) protein, a transcription factor that acts as a positive regulator of insulin gene transcription. Promotes the expression of islet genes.
A: The LMX1A gene plays a role in the development of dopamine-producing neurons during embryonic development.
A: Lmx1a and Lmx1b expression is present in mature dopaminergic neurons in the substantia nigra densa and ventral tegmental area. SNPs in the LMX1A gene may be associated with susceptibility to congenital scoliosis and different clinical phenotypes in the Chinese Han population.
A: At the metastatic stage of official precancer, LMX1A was less methylation in cervical adenocarcinoma compared with controls. The higher expression was associated with more advanced tumor stage in Chinese patients with pancreatic ductal adenocarcinoma.
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It only needs to be diluted according to the dilution ratio for different experiments and then it can be used.
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