Human IL7R mRNA

Name: Human IL7R mRNA
SKU: PMRN-0218

For research use only. Not intended for any clinical use.

Cat.No.

PMRN-0218

Description

The IL7R mRNA encodes the human interleukin 7 receptor (IL7R) protein, a receptor for interleukin 7 (IL7). IL7R has been shown to play a critical role in V(D)J recombination during lymphocyte development.

Alias

ILRA; CD127; IL7RA; CDW127; IL-7R-alpha

Features

• mRNA synthesized on error free sequence verified plasmid DNA template
• 100% replacement of UTP with modified nucleotides 5-Methoxy-UTP
• Cap 1 Capping and poly-A tailed incorporated
• Degrades the DNA template after RNA synthesis with DNase

Sequence

MTILGTTFGM VFSLLQVVSG ESGYAQNGDL EDAELDDYSF SCYSQLEVNG SQHSLTCAFE DPDVNTTNLE FEICGALVEV KCLNFRKLQE IYFIETKKFL LIGKSNICVK VGEKSLTCKK IDLTTIVKPE APFDLSVIYR EGANDFVVTF NTSHLQKKYV KVLMHDVAYR QEKDENKWTH VNLSSTKLTL LQRKLQPAAM YEIKVRSIPD HYFKGFWSEW SPSYYFRTPE INNSSGEMDP ILLTISILSF FSVALLVILA CVLWKKRIKP IVWPSLPDHK KTLEHLCKKP RKNLNVSFNP ESFLDCQIHR VDDIQARDEV EGFLQDTFPQ QLEESEKQRL GGDVQSPNCP SEDVVITPES FGRDSSLTCL AGNVSACDAP ILSSSRSLDC RESGKNGPHV YQDLLLSLGT TNSTLPPPFS LQSGILTLNP VAQGQPILTS LGSNQEEAYV TMSSFYQNQ

Species

Homo sapiens (Human)

Storage

Store at or below -70°C. Avoid repeated freeze/thaw cycles. Aliquot if necessary using RNase-free equipment, reagents, pipet tips, tubes, and containers.

Publications

Q & A

Customer Reviews

Customer Q&As

What is Human IL7R mRNA?

A: Human IL7R mRNA is the messenger RNA of the human IL7R gene. IL7R (interleukin-7 receptor) is a cell surface receptor that binds to interleukin-7 (IL-7) and plays a crucial role in the development and survival of lymphocytes.

What is the role of Human IL7R mRNA in the human body?

A: The function of Human IL7R mRNA is to encode the IL7R protein. After binding with IL-7, IL7R can promote the survival, proliferation, and differentiation of lymphocytes, playing an important regulatory role in the formation of lymphocytes and the function of the immune system.

In which cells is Human IL7R mRNA expressed?

A: Human IL7R mRNA is mainly expressed in lymphocytes, including T cells, B cells, and NK cells. In addition, it is also expressed in certain tumor cells and hematopoietic stem cells.

How to treat diseases by regulating the expression of Human IL7R mRNA?

A: The expression of Human IL7R mRNA can be regulated through methods such as medication or gene therapy. For example, the use of inhibitors can inhibit the expression of IL7R, thereby alleviating inflammatory and immune responses, and alleviating symptoms of the disease. Meanwhile, gene knockout or RNA interference techniques can reduce the expression level of IL7R, providing new ideas and methods for the treatment of some inflammatory and immune related diseases. In addition, supplementing with IL-7 to stimulate lymphocyte proliferation and differentiation is also a potential therapeutic approach.

What are the ligands of Human IL7R?

A: The ligands of Human IL7R include interleukin-7 (IL-7). After binding to IL7R, IL-7 can trigger a series of signal transduction pathways, playing an important regulatory role in the survival, proliferation, and differentiation of lymphocytes.

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