Human IL5 mRNA

Name: Human IL5 mRNA
SKU: PMRN-0143

For research use only. Not intended for any clinical use.

Cat.No.

PMRN-0143

Description

The IL5 mRNA encodes the human interleukin 5 (IL5) protein, a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. IL5 plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases.

Alias

EDF, IL-5, TRF

Features

• mRNA synthesized on error free sequence verified plasmid DNA template
• 100% replacement of UTP with modified nucleotides 5-Methoxy-UTP
• Cap 1 Capping and poly-A tailed incorporated
• Degrades the DNA template after RNA synthesis with DNase

Sequence

MRMLLHLSLL ALGAAYVYAI PTEIPTSALV KETLALLSTH RTLLIANETL RIPVPVHKNH QLCTEEIFQG IGTLESQTVQ GGTVERLFKN LSLIKKYIDG QKKKCGEERR RVNQFLDYLQ EFLGVMNTEW IIES

Species

Homo sapiens (Human)

Storage

Store at or below -70°C. Avoid repeated freeze/thaw cycles. Aliquot if necessary using RNase-free equipment, reagents, pipet tips, tubes, and containers.

Publications

Q & A

Customer Reviews

Customer Q&As

What is Human IL5 mRNA?

A: Human IL5 mRNA is a type of mRNA encoded by human genes, derived from the interleukin-5 (IL5) gene.

What diseases are associated with Human IL5 mRNA?

A: Research has shown that Human IL5 mRNA may be associated with various diseases, including but not limited to asthma, chronic obstructive pulmonary disease, nasal polyps, etc. The protein encoded by this gene is an interleukin that can regulate the activation and function of eosinophils, participate in immune and inflammatory responses.

What is the IL5 gene?

A: The IL5 gene is a human gene that encodes a protein called interleukin, also known as IL-5. It can regulate the growth, differentiation, and function of eosinophils, participate in biological processes such as immune response and inflammatory response.

What is the role of Human IL5 mRNA in diseases?

A: Research has shown that Human IL5 mRNA may play an important role in the occurrence and development of diseases. The protein it encodes is an interleukin that can regulate the activation and function of eosinophils, promote inflammation and tissue damage, etc. The expression level of this gene may be related to the severity and prognosis of the disease.

Which chromosome is this gene located on?

A: This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2 . This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.

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