Human IL33 mRNA

Name: Human IL33 mRNA
SKU: PMRN-0168

For research use only. Not intended for any clinical use.

Cat.No.

PMRN-0168

Description

The IL33 mRNA encodes the human interleukin 33 (IL33) protein, a cytokine that binds to the IL1RL1/ST2 receptor. IL33 is involved in the maturation of Th2 cells and the activation of mast cells, basophils, eosinophils and natural killer cells.

Alias

DVS27; IL1F11; NF-HEV; NFEHEV; C9orf26

Features

• mRNA synthesized on error free sequence verified plasmid DNA template
• 100% replacement of UTP with modified nucleotides 5-Methoxy-UTP
• Cap 1 Capping and poly-A tailed incorporated
• Degrades the DNA template after RNA synthesis with DNase

Sequence

MKPKMKYSTN KISTAKWKNT ASKALCFKLG KSQQKAKEVC PMYFMKLRSG LMIKKEACYF RRETTKRPSL KTGRKHKRHL VLAACQQQST VECFAFGISG VQKYTRALHD SSITGISPIT EYLASLSTYN DQSITFALED ESYEIYVEDL KKDEKKDKVL LSYYESQHPS NESGDGVDGK MLMVTLSPTK DFWLHANNKE HSVELHKCEK PLPDQAFFVL HNMHSNCVSF ECKTDPGVFI GVKDNHLALI KVDSSENLCT ENILFKLSET

Species

Homo sapiens (Human)

Storage

Store at or below -70°C. Avoid repeated freeze/thaw cycles. Aliquot if necessary using RNase-free equipment, reagents, pipet tips, tubes, and containers.

Publications

Q & A

Customer Reviews

Customer Q&As

What is Human IL33 mRNA?

A: Human IL33 mRNA is a molecule that encodes human interleukin-33 (IL-33). IL-33 is a cytokine that plays an important role in the immune system.

What is the main function of Human IL33 mRNA?

A: The main function of Human IL33 mRNA is to produce and secrete IL-33, a cytokine that plays a crucial role in immune and inflammatory responses.

In which cells is Human IL33 mRNA expressed?

A: Human IL33 mRNA can be expressed in various cells, including bone marrow stromal cells, epithelial cells, endothelial cells, adipocytes, and fibroblasts.

What diseases are associated with Human IL33 mRNA?

A: Research has shown that Human IL33 mRNA is associated with various autoimmune diseases, inflammatory diseases, and cardiovascular diseases. For example, IL-33 may be involved in the pathogenesis of inflammatory diseases such as rheumatoid arthritis, systemic lupus erythematosus, and bronchial asthma.

How to use Human IL33 mRNA for disease treatment?

A: The therapeutic strategies for Human IL33 mRNA include inhibiting its expression, regulating its function, and utilizing it as a biomarker. For example, inhibiting the expression of IL-33 can treat inflammatory diseases related to IL-33. In addition, by developing drugs targeting IL-33 receptors, they can also be used to treat related diseases.

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