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Human IL27 mRNA

For research use only. Not intended for any clinical use.
Cat.No.
PMRN-0165
Description
The IL27 mRNA encodes the human interleukin 27 (IL27) protein, one of the subunits of a heterodimeric cytokine complex. IL-27 has pro- and anti-inflammatory properties, that can regulate T-helper cell development, suppress T-cell proliferation, stimulate cytotoxic T-cell activity and induce isotype switching in B-cells.
Alias
p28; IL30; IL-27; IL27A; IL-27A; IL27p28
Features
• mRNA synthesized on error free sequence verified plasmid DNA template
• 100% replacement of UTP with modified nucleotides 5-Methoxy-UTP
• Cap 1 Capping and poly-A tailed incorporated
• Degrades the DNA template after RNA synthesis with DNase
Sequence
MGQTAGDLGW RLSLLLLPLL LVQAGVWGFP RPPGRPQLSL QELRREFTVS LHLARKLLSE VRGQAHRFAE SHLPGVNLYL LPLGEQLPDV SLTFQAWRRL SDPERLCFIS TTLQPFHALL GGLGTQGRWT NMERMQLWAM RLDLRDLQRH LRFQVLAAGF NLPEEEEEEE EEEEEERKGL LPGALGSALQ GPAQVSWPQL LSTYRLLHSL ELVLSRAVRE LLLLSKAGHS VWPLGFPTLS PQP
Species
Homo sapiens (Human)
Storage
Store at or below -70°C. Avoid repeated freeze/thaw cycles. Aliquot if necessary using RNase-free equipment, reagents, pipet tips, tubes, and containers.

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Q & A

Customer Reviews

Customer Q&As
What is Human IL27 mRNA?

A: Human IL27 mRNA is a messenger RNA molecule encoding the human interleukin-27 protein in the human body.

What is the function of Human IL27 mRNA?

A: The protein encoded by Human IL27 mRNA is a cytokine that can regulate the function of the immune system, promote the development and activation of T cells, and inhibit inflammatory responses.

In which tissues is Human IL27 mRNA expressed?

A: Human IL27 mRNA is expressed in various tissues, including lymphatic tissue in the immune system, spleen, lungs, liver, kidneys, etc.

What is the regulation of human IL27 mRNA production?

A: The production of Human IL27 mRNA is regulated by various signaling pathways, including inflammation signaling, cytokine signaling, and the activation status of immune cells.

What diseases are associated with abnormal expression of Human IL27 mRNA?

A: The abnormal expression of Human IL27 mRNA is associated with various diseases, including inflammatory diseases, autoimmune diseases, tumors, etc.

How to detect the expression level of Human IL27 mRNA?

A: Real time fluorescence quantitative PCR (qPCR) or gene chip methods can be used to detect the expression level of HumanIL27 mRNA.

What is the degradation rate of Human IL27 mRNA?

A: The degradation rate of Human IL27 mRNA is influenced by various factors, including cell type, environmental conditions, and RNA structure.

Is there a treatment method for Human IL27mRNA?

A: At present, there is no direct treatment method for Human IL27 mRNA, but it can be achieved by regulating the immune system to affect its function and thus treat related diseases.

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Customer Reviews
Time saving

There is no need for a lot of sample pre-treatment such as heating and centrifugation as in other similar commercial kits. Just dissolve the product directly for mouse injection.

United States

01/27/2022

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