Transfected Stable Cell Lines
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Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : PMRN-0072
| Cat. No. | PMRN-0072 |
| Description | The FGF12 mRNA encodes the human fibroblast growth factor 12 (FGF12) protein, a member of the fibroblast growth factor (FGF) family. FGF12 probably involves in nervous system development and function, and the positive regulation of voltage-gated sodium channel activity. |
| Gene Type | Other |
| RNA Type | mRNA |
| Gene Name | FGF12 |
| Species | Homo sapiens (Human) |
| Alias | DEE47, EIEE47, FGF12B, FHF1 |
| Features |
• mRNA synthesized on error free sequence verified plasmid DNA template • 100% replacement of UTP with modified nucleotides 5-Methoxy-UTP • Cap 1 Capping and poly-A tailed incorporated • Degrades the DNA template after RNA synthesis with DNase |
| Sequence | MAAAIASSLI RQKRQARESN SDRVSASKRR SSPSKDGRSL CERHVLGVFS KVRFCSGRKR PVRRRPEPQL KGIVTRLFSQ QGYFLQMHPD GTIDGTKDEN SDYTLFNLIP VGLRVVAIQG VKASLYVAMN GEGYLYSSDV FTPECKFKES VFENYYVIYS STLYRQQESG RAWFLGLNKE GQIMKGNRVK KTKPSSHFVP KPIEVCMYRE PSLHEIGEKQ GRSRKSSGTP TMNGGKVVNQ DST |
| Storage | Store at or below -70°C. Avoid repeated freeze/thaw cycles. Aliquot if necessary using RNase-free equipment, reagents, pipet tips, tubes, and containers. |
A: FGF12 mRNA encodes human fibroblast growth factor 12 (FGF12) protein, a member of the fibroblast growth factor (FGF) family.
A: FGF12 may be involved in the development and function of the nervous system and the positive regulation of voltage-gated sodium channel activity.
A: Disorders associated with FGF12 include developmental and epileptic encephalopathy47 and nonspecific early-onset epileptic encephalopathy. Its related pathways include the apoptotic pathway and GPCR pathway in synovial fibroblasts.
A: Although FGF21 signaling can promote post-translational protein modifications60,61 and alter gene expression62,63, little is known about intracellular signaling pathways and intracellular FGF21 mechanisms of action.
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Covers a wide range of sensitivities. The work of b expression regulation assay of liver signal peptide using Human FGF12 mRNA does not require special instrumentation, just a follow the routine steps of injection experiment. This is your best choice when you have limited experimental conditions.
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