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Human CCL22 mRNA

For research use only. Not intended for any clinical use.

Cat. No. :   PMRN-0131

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Product Information

Cat. No. PMRN-0131
Description The CCL22 mRNA encodes the human C-C motif chemokine ligand 22 (CCL22) protein, a cytokine that displays chemotactic activity for monocytes, dendritic cells, natural killer cells and for chronically activated T lymphocytes. CCL22 also displays a mild activity for primary activated T lymphocytes and has no chemoattractant activity for neutrophils, eosinophils and resting T lymphocytes.
Gene Type Other
RNA Type mRNA
Gene Name CCL22
Species Homo sapiens (Human)
Alias A-152E5.1, ABCD-1, DC/B-CK, MDC, SCYA22, STCP-1
Features • mRNA synthesized on error free sequence verified plasmid DNA template
• 100% replacement of UTP with modified nucleotides 5-Methoxy-UTP
• Cap 1 Capping and poly-A tailed incorporated
• Degrades the DNA template after RNA synthesis with DNase
Sequence MDRLQTALLV VLVLLAVALQ ATEAGPYGAN MEDSVCCRDY VRYRLPLRVV KHFYWTSDSC PRPGVVLLTF RDKEICADPR VPWVKMILNK LSQ
Storage Store at or below -70°C. Avoid repeated freeze/thaw cycles. Aliquot if necessary using RNase-free equipment, reagents, pipet tips, tubes, and containers.
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Customer Q&As
What protein does human CCL22 mRNA encode?

A: CCL22 mRNA encodes human C-C patterned chemokine ligand 22 (CCL22) protein, a cytokine that displays chemotactic activity against monocytes, dendritic cells, natural killer cells and chronically activated T lymphocytes.

What physiological activities are human CCL22 mRNAs involved in?

A: The product of the CCL22 gene binds to the chemokine receptor CCR4. This chemokine may play a role in the transport of activated T lymphocytes to sites of inflammation and other aspects of activated T lymphocyte physiology.

What is the role of CCL22 mRNA in different immune cells?

A: The CCL22 mRNA showed mild activity against primary activated T lymphocytes and no chemoattractive activity against neutrophils, eosinophils and resting T lymphocytes.

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Customer Reviews
Good experimental results

I feel that the purity of the product is still very high, and the expressed CCL22 mRNA can make the downstream protein expression reach the expected level. Three parallel experiments were done with consistent results, which is very good.

United States

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