Transfected Stable Cell Lines
Reliable | High-Performance | Wide Rage
Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : PMRN-0131
| Cat. No. | PMRN-0131 |
| Description | The CCL22 mRNA encodes the human C-C motif chemokine ligand 22 (CCL22) protein, a cytokine that displays chemotactic activity for monocytes, dendritic cells, natural killer cells and for chronically activated T lymphocytes. CCL22 also displays a mild activity for primary activated T lymphocytes and has no chemoattractant activity for neutrophils, eosinophils and resting T lymphocytes. |
| Gene Type | Other |
| RNA Type | mRNA |
| Gene Name | CCL22 |
| Species | Homo sapiens (Human) |
| Alias | A-152E5.1, ABCD-1, DC/B-CK, MDC, SCYA22, STCP-1 |
| Features |
• mRNA synthesized on error free sequence verified plasmid DNA template • 100% replacement of UTP with modified nucleotides 5-Methoxy-UTP • Cap 1 Capping and poly-A tailed incorporated • Degrades the DNA template after RNA synthesis with DNase |
| Sequence | MDRLQTALLV VLVLLAVALQ ATEAGPYGAN MEDSVCCRDY VRYRLPLRVV KHFYWTSDSC PRPGVVLLTF RDKEICADPR VPWVKMILNK LSQ |
| Storage | Store at or below -70°C. Avoid repeated freeze/thaw cycles. Aliquot if necessary using RNase-free equipment, reagents, pipet tips, tubes, and containers. |
A: CCL22 mRNA encodes human C-C patterned chemokine ligand 22 (CCL22) protein, a cytokine that displays chemotactic activity against monocytes, dendritic cells, natural killer cells and chronically activated T lymphocytes.
A: The product of the CCL22 gene binds to the chemokine receptor CCR4. This chemokine may play a role in the transport of activated T lymphocytes to sites of inflammation and other aspects of activated T lymphocyte physiology.
A: The CCL22 mRNA showed mild activity against primary activated T lymphocytes and no chemoattractive activity against neutrophils, eosinophils and resting T lymphocytes.
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I feel that the purity of the product is still very high, and the expressed CCL22 mRNA can make the downstream protein expression reach the expected level. Three parallel experiments were done with consistent results, which is very good.
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