Human ACVR1B mRNA

Name: Human ACVR1B mRNA
SKU: PMRN-0243

For research use only. Not intended for any clinical use.

Cat.No.

PMRN-0243

Description

The ACVR1B mRNA encodes the human activin A receptor type 1B (ACVR1B) protein, a type I receptor which is essential for signaling.

Alias

ACTRIB, ACVRLK4, ALK4, SKR2

Features

• mRNA synthesized on error free sequence verified plasmid DNA template
• 100% replacement of UTP with modified nucleotides 5-Methoxy-UTP
• Cap 1 Capping and poly-A tailed incorporated
• Degrades the DNA template after RNA synthesis with DNase

Sequence

MAESAGASSF FPLVVLLLAG SGGSGPRGVQ ALLCACTSCL QANYTCETDG ACMVSIFNLD GMEHHVRTCI PKVELVPAGK PFYCLSSEDL RNTHCCYTDY CNRIDLRVPS GHLKEPEHPS MWGPVELVGI IAGPVFLLFL IIIIVFLVIN YHQRVYHNRQ RLDMEDPSCE MCLSKDKTLQ DLVYDLSTSG SGSGLPLFVQ RTVARTIVLQ EIIGKGRFGE VWRGRWRGGD VAVKIFSSRE ERSWFREAEI YQTVMLRHEN ILGFIAADNK DNGTWTQLWL VSDYHEHGSL FDYLNRYTVT IEGMIKLALS AASGLAHLHM EIVGTQGKPG IAHRDLKSKN ILVKKNGMCA IADLGLAVRH DAVTDTIDIA PNQRVGTKRY MAPEVLDETI NMKHFDSFKC ADIYALGLVY WEIARRCNSG GVHEEYQLPY YDLVPSDPSI EEMRKVVCDQ KLRPNIPNWW QSYEALRVMG KMMRECWYAN GAARLTALRI KKTLSQLSVQ EDVKI

Species

Homo sapiens (Human)

Storage

Store at or below -70°C. Avoid repeated freeze/thaw cycles. Aliquot if necessary using RNase-free equipment, reagents, pipet tips, tubes, and containers.

Publications

Q & A

Customer Reviews

Customer Q&As

What is Human ACVR1B mRNA?

A: Human ACVR1B mRNA is a messenger RNA of the human ACVR1B gene. ACVR1B (Activin Receptor like Kinase 1) is a cell surface receptor that, after binding to ligands such as Activin, participates in processes such as cell proliferation, differentiation, and apoptosis.

What is the role of Human ACVR1B mRNA in the human body?

A: The function of Human ACVR1B mRNA is to encode the ACVR1B protein. After binding with ligands such as activin, ACVR1B can trigger a series of signal transduction pathways to regulate the biological behavior of cells, including cell proliferation, differentiation, apoptosis, etc. In addition, ACVR1B is also involved in the occurrence and development of certain neurological diseases, tumors, and other diseases.

In which cells is Human ACVR1B mRNA expressed?

A: Human ACVR1B mRNA is expressed in various cells, including liver cells, kidney cells, myocardial cells, neurons, etc. In addition, it is also expressed in certain tumor cells.

How is the expression of Human ACVR1B mRNA regulated?

A: The expression of Human ACVR1B mRNA is regulated by various factors, including transcription factors, signal transduction pathways, and induction or inhibition of some cytokines. In addition, the concentration of activin can also affect the expression level of ACVR1B.

What diseases are associated with Human ACVR1B mRNA?

A: Research has shown that Human ACVR1B mRNA is associated with some neurological diseases, tumors, and some autoimmune diseases. In these diseases, the expression level of ACVR1B may change, thereby affecting the progression and prognosis of the disease. In addition, abnormalities in the ACVR1B signaling pathway may also lead to the occurrence of certain genetic diseases.

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