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human DOCK4 (NM_014705) lentivirus particles

For research use only. Not intended for any clinical use.

Cat. No. :   LV11051L

Storage :   -80℃ Shipping :   Frozen on dry ice

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Virus Particles Information

Quality Control

Gene Information

Cat. No. LV11051L
Description Lentiviral particles of dedicator of cytokinesis 4 (DOCK4).
Product Type Premade Lentivirus Particles
Gene DOCK4
Species Human
Insert Size 5901 bp
Titer Varies lot by lot, for example, ≥1*10^7 TU/mL, ≥1*10^8 TU/mL, ≥1*10^9 TU/mL etc.
Size Varies lot by lot, for example, 100 ul, 500 ul, 1 mL etc.
Storage Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping Frozen on dry ice
Summary Creative Biogene ensures high-quality lentivirus particles by optimizing and standardizing production protocols and performing stringent quality control (QC). The specific QC experiments performed vary between lentivirus particle lots.
Mycoplasma Creative Biogene routinely tests for mycoplasma contamination using a mycoplasma detection kit. Cell lines are maintained for approximately 20 passages before being discarded and replaced with a new vial of early passage cells. Approximately 2 weeks after thawing, cell culture supernatants are tested for mycoplasma contamination. Creative Biogene ensures that lentiviral products are free of mycoplasma contamination.
Purity Creative Biogene evaluates the level of impurities, such as residual host cell DNA or proteins, in prepared lentiviral vectors to ensure they meet quality standards.
Sterility The lentiviral samples were inoculated into cell culture medium for about 5 days and the growth of bacteria and fungi was tested. Creative Biogene ensures that the lentiviral products are free of microbial contamination.
Transducibility Upon requirement, Creative Biogene can perform in vitro or in vivo transduction assays to evaluate the ability of lentivirus to deliver genetic material into target cells, and assess gene expression and functional activities.
Proviral Identity Confirmation All Creative Biogene lentiviral vectors are confirmed to have correctly integrated provirus using PCR. This test involves transducing cells with serial dilutions of the lentiviral vector, harvesting the cells a few days later, and isolating genomic DNA. This DNA is then used as a template to amplify a portion of the expected lentiviral insert.
Gene Name DOCK4 dedicator of cytokinesis 4 [ Homo sapiens ]
Gene Symbol DOCK4
Gene Description dedicator of cytokinesis 4
Gene ID 9732
Uni Prot ID Q8N1I0
m RNA Refseq NM_014705.3
Protein Refseq NP_055520.3
Chromosome Location 7q31.1
Function GTP binding; PDZ domain binding; Rac GTPase activator activity; Rac GTPase binding; SH3 domain binding; guanyl-nucleotide exchange factor activity; protein binding; receptor tyrosine kinase binding;
Pathway Factors involved in megakaryocyte development and platelet production, organism-specific biosystem; Hemostasis, organism-specific biosystem;
MIM 607679
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