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shRNA set against Human DOCK4 (NM_014705.3)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH280193

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Gene Information

Cat. No. SHH280193
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr DOCK4
Gene Name DOCK4 dedicator of cytokinesis 4 [ Homo sapiens ]
Species Human
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name DOCK4 dedicator of cytokinesis 4 [ Homo sapiens ]
Gene Symbol DOCK4
Gene Description dedicator of cytokinesis 4
Gene ID 9732
Uni Prot ID Q8N1I0
m RNA Refseq NM_014705.3
Protein Refseq NP_055520.3
Chromosome Location 7q31.1
Function GTP binding; PDZ domain binding; Rac GTPase activator activity; Rac GTPase binding; SH3 domain binding; guanyl-nucleotide exchange factor activity; protein binding; receptor tyrosine kinase binding;
Pathway Factors involved in megakaryocyte development and platelet production, organism-specific biosystem; Hemostasis, organism-specific biosystem;
MIM 607679
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