GFP/Luc Reporter Cell Line - SU-DHL-1

SU-DHL-1 is a histiocyte isolated from the lymph node of a 10-year-old Caucasian male patient with large cell lymphoma. Interestingly, their ability to phagocytose C. albicans and latex particles makes them important in the study of cellular immunity. These cells were reported to be very weakly E-rosette positive. This means they bind weakly to red blood cells, a process common in T lymphocytes. GFP/Luc Reporter Cell Line - SU-DHL-1 is a scientifically engineered cell line widely used in biological and medical research. The SU-DHL-1 cell line has been modified to express GFP (green fluorescent protein) and luciferase (Luc). GFP is a protein that exhibits bright green fluorescence when exposed to light in the blue to ultraviolet range. Its expression provides an efficient method to monitor spatial patterns of gene expression and protein localization in real time, making it an important tool in cellular and molecular biology research. Luciferase acts as a reporter gene, allowing researchers to non-invasively visualize and monitor biological processes within living cells. It helps measure transcriptional activity in cell lines, providing valuable insights into gene function and the impact of various pharmaceutical compounds on this process.