Rat Uba3 cDNA Clone(NM_057205.2)

Name: Rat Uba3 cDNA Clone(NM_057205.2)
SKU: CDFR013783
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR013783

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Product Information

Gene Information

Cat. No.	CDFR013783
Description	NativeORF clone of Rattus norvegicus ubiquitin-like modifier activating enzyme 3 (Uba3) as transfection-ready DNA NM_057205.2
Product Type	cDAN Clone
Gene Abbr	Uba3
Species	Rat
Vector	pCMV6Entry

Target Gene

UBA3

Background

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme associates with AppBp1, an amyloid beta precursor protein binding protein, to form a heterodimer, and then the enzyme complex activates NEDD8, a ubiquitin-like protein, which regulates cell division, signaling and embryogenesis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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