Panoply™ Human UBA3 Knockdown Stable Cell Line

Name: Panoply™ Human UBA3 Knockdown Stable Cell Line
SKU: CSC-DC016931
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC016931

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC016931
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	UBA3
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	UBA3 ubiquitin-like modifier activating enzyme 3 [ Homo sapiens ]
Gene Symbol	UBE1C
Synonyms	UBE1C; hUBA3
Gene Description	ubiquitin-activating enzyme E1C (UBA3 homolog, yeast)
GeneID	9039
Uni ProtID	Q8TBC4
mRNA Refseq	NM_198195.1
Protein Refseq	NP_937838.1
Chromosome Location	3p24.3-p13
Function	ATP binding; NEDD8 activating enzyme activity; acid-amino acid ligase activity; protein binding; protein heterodimerization activity;
Pathway	Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination & Proteasome degradation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; Coregulation of Androgen receptor activity, organism-specific biosystem; Immune System, organism-specific biosystem;
MIM	603172

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