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Human UBA3 cDNA Clone(NM_003968.3)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFH020709

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Gene Information

Cat. No. CDFH020709
Product Type cDNA clone
Gene Abbr UBA3
Species Human
Size 10 ug
Vector pCMV6-XL5
Target Gene UBA3
Background The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme associates with AppBp1, an amyloid beta precursor protein binding protein, to form a heterodimer, and then the enzyme complex activates NEDD8, a ubiquitin-like protein, which regulates cell division, signaling and embryogenesis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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