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Rat Tnfrsf10b cDNA Clone(NM_001108873.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR008441

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Gene Information

Cat. No. CDFR008441
Description NativeORF clone of Rattus norvegicus tumor necrosis factor receptor superfamily, member 10b (Tnfrsf10b) as transfection-ready DNA NM_001108873.1
Product Type cDAN Clone
Gene Abbr Tnfrsf10b
Species Rat
Target Gene TNFRSF10B
Background The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009]
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