Transfected Stable Cell Lines
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Cat. No. : CDCL186525
| Cat. No. | CDCL186525 |
| Description | ORF Clone of Mus musculus tumor necrosis factor receptor superfamily, member 10b DNA. |
| Product Type | ORF clone |
| Gene Abbr | TNFRSF10B |
| Species | Mouse |
| ORF Size | 1146bp |
| Vector | pGEM-T |
| Warning | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Storage | store at -20°C |
| Target Gene | TNFRSF10B |
| Background | The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009] |
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