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Mouse TNFRSF10B ORF clone(NM_020275.4)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCL186525

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Product Information

Gene Information

Cat. No. CDCL186525
Description ORF Clone of Mus musculus tumor necrosis factor receptor superfamily, member 10b DNA.
Product Type ORF clone
Gene Abbr TNFRSF10B
Species Mouse
ORF Size 1146bp
Vector pGEM-T
Warning This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Storage store at -20°C
Target Gene TNFRSF10B
Background The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009]
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