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Human TNFRSF10B Knockdown Cell Line-HeLa

Cat.No.
CSC-RK0294
Abbr
HeLa-HuTNFRSF10B Knockdown
Alias
TNFRSF10B,CD262,DR5,KILLER,TRAIL R2,TRICK2A,TRICKB,TRICK2,ZTNFR9,TRAILR2,TRICK2B,TRAIL-R2,KILLER/DR5,
Growth Properties
Adherent
Host Cell
HeLa
Morphology
Epithelial
Shipping
Dry ice
Species
Human
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.

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