Rat Tap1 cDNA Clone(NM_032055.4)

Name: Rat Tap1 cDNA Clone(NM_032055.4)
SKU: CDFR012993
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR012993

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Product Information

Gene Information

Cat. No.	CDFR012993
Description	NativeORF clone of Rattus norvegicus transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) (Tap1) as transfection-ready DNA NM_032055.4
Product Type	cDAN Clone
Gene Abbr	Tap1
Species	Rat
Vector	pCMV6Entry

Target Gene

TAP1

Background

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is involved in the pumping of degraded cytosolic peptides across the endoplasmic reticulum into the membrane-bound compartment where class I molecules assemble. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014]

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