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Panoply™ Human TAP1 Knockdown Stable Cell Line

Cat.No.
CSC-DC015576
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
TAP1
Synonyms
APT1; PSF1; ABC17; ABCB2; PSF-1; RING4; TAP1N; D6S114E; TAP1*0102N
Gene Description
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
Gene ID
UniProt ID
Q03518
mRNA Refseq
Protein Refseq
Chromosome Location
6p21.3
Function
ADP binding; ATP binding; MHC class I protein binding; TAP1 binding; TAP1 binding; TAP2 binding; TAP2 binding; oligopeptide-transporting ATPase activity; peptide antigen binding; peptide antigen binding; contributes_to peptide transporter activity; peptide transporter activity; protein binding; protein heterodimerization activity; protein homodimerization activity; tapasin binding;
Pathway
ABC transporters, organism-specific biosystem; ABC transporters, conserved biosystem; Adaptive Immune System, organism-specific biosystem; Antigen Presentation: Folding, assembly and peptide loading of class I MHC, organism-specific biosystem; Antigen processing and presentation, organism-specific biosystem; Antigen processing and presentation, conserved biosystem; Antigen processing-Cross presentation, organism-specific biosystem;
MIM

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