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Mouse Tap1 cDNA Clone(NM_013683.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFL013435

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Product Information

Gene Information

Cat. No. CDFL013435
Product Type cDNA clone
Gene Abbr Tap1
Species Mouse
Size 10 ug
Vector pCMV6Entry
Target Gene TAP1
Background The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is involved in the pumping of degraded cytosolic peptides across the endoplasmic reticulum into the membrane-bound compartment where class I molecules assemble. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014]
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