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Rat Tank cDNA Clone(NM_145788.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR014526

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Gene Information

Cat. No. CDFR014526
Description NativeORF clone of Rattus norvegicus TRAF family member-associated NFKB activator (Tank) as transfection-ready DNA NM_145788.2
Product Type cDAN Clone
Gene Abbr Tank
Species Rat
Vector pCMV6Entry
Target Gene TANK
Background The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. The protein encoded by this gene is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, the protein encoded by this gene can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
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