Rat TANK ORF clone(NM_001164073.1)

Name: Rat TANK ORF clone(NM_001164073.1)
SKU: CDCH016712
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCH016712

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Product Information

Gene Information

Cat. No.	CDCH016712
Product Type	ORF clone
Gene Abbr	TANK
Species	Rat
Host Cell	Bacterial
Source	Bacterial
ORF Size	2066bp
Size	1ug
Format	Clear Liquid
Vector	pORF
Buffer	10mM Tris-HCI, 1mM EDTA, pH8.0
Warning	pORF-rTank ORF Vector is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information.
Storage	1 year when stored at -20°C or lower in a non-frost free freezer.

Target Gene

TANK

Background

The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. The protein encoded by this gene is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, the protein encoded by this gene can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]

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