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Rat Smad3 cDNA Clone(NM_013095.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR010896

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Gene Information

Cat. No. CDFR010896
Description NativeORF clone of Rattus norvegicus SMAD family member 3 (Smad3) as transfection-ready DNA NM_013095.2
Product Type cDAN Clone
Gene Abbr Smad3
Species Rat
Vector pCMV6Entry
Target Gene SMAD3
Background The SMAD family of proteins are a group of intracellular signal transducer proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. The SMAD3 protein functions in the transforming growth factor-beta signaling pathway, and transmits signals from the cell surface to the nucleus, regulating gene activity and cell proliferation. This protein forms a complex with other SMAD proteins and binds DNA, functioning both as a transcription factor and tumor suppressor. Mutations in this gene are associated with aneurysms-osteoarthritis syndrome and Loeys-Dietz Syndrome 3. [provided by RefSeq, May 2022]
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