Mouse Smad3 Insect Cell Lysate

Name: Mouse Smad3 Insect Cell Lysate
SKU: CLOE-2362
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CLOE-2362 Host Cell : Baculovirus-Insect cell

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Cell Lysate Information

Gene Information

Cat. No.	CLOE-2362
Introduction	This cell lysate over-expresses mouse Smad3 (P84025) (Met1-Ser425) fused with N-terminal His/GST tag. Purification of target protein (s) from this cell lysate has been verified.
Target Gene	Smad3
Host Cell	Baculovirus-Insect cell
Applications	Positive control for Western Blot (WB), antibody verification, protein purification
Storage	Upon receipt, store at 4°C, or prepare aliquots and store at -80°C. Multiple freeze-thaw cycles should be avoided.
Shipping	Ice package

Target Gene

SMAD3

Background

The SMAD family of proteins are a group of intracellular signal transducer proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. The SMAD3 protein functions in the transforming growth factor-beta signaling pathway, and transmits signals from the cell surface to the nucleus, regulating gene activity and cell proliferation. This protein forms a complex with other SMAD proteins and binds DNA, functioning both as a transcription factor and tumor suppressor. Mutations in this gene are associated with aneurysms-osteoarthritis syndrome and Loeys-Dietz Syndrome 3. [provided by RefSeq, May 2022]

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