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Rat Plod3 cDNA Clone(NM_178101.3)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR014917

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Gene Information

Cat. No. CDFR014917
Description NativeORF clone of Rattus norvegicus procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 (Plod3) as transfection-ready DNA NM_178101.3
Product Type cDAN Clone
Gene Abbr Plod3
Species Rat
Vector pCMV6Entry
Target Gene PLOD3
Background The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. [provided by RefSeq, Jul 2008]
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