Transfected Stable Cell Lines
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Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CDFR014917
| Cat. No. | CDFR014917 |
| Description | NativeORF clone of Rattus norvegicus procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 (Plod3) as transfection-ready DNA NM_178101.3 |
| Product Type | cDAN Clone |
| Gene Abbr | Plod3 |
| Species | Rat |
| Vector | pCMV6Entry |
| Target Gene | PLOD3 |
| Background | The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. [provided by RefSeq, Jul 2008] |
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