Mouse PLOD3 ORF clone(NM_011962.3)

Name: Mouse PLOD3 ORF clone(NM_011962.3)
SKU: CDCG003389
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCG003389

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Product Information

Gene Information

Cat. No.	CDCG003389
Product Type	ORF clone
Gene Abbr	PLOD3
Species	Mouse
Host Cell	Bacterial
Source	Bacteria
ORF Size	3278bp
Size	1ug
Format	Clear Liquid
Vector	pORF
Buffer	10mM Tris-HCI, 1mM EDTA, pH8.0
Warning	pORF-mPlod3 ORF Vector is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information.
Storage	1 year when stored at -20°C or lower in a non-frost free freezer.

Target Gene

PLOD3

Background

The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. [provided by RefSeq, Jul 2008]

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