Rat Nfkb2 cDNA Clone(NM_001008349.1)

Name: Rat Nfkb2 cDNA Clone(NM_001008349.1)
SKU: CDFR001811
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR001811

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Product Information

Gene Information

Cat. No.	CDFR001811
Description	NativeORF clone of Rattus norvegicus nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 (Nfkb2) as transfection-ready DNA NM_001008349.1
Product Type	cDAN Clone
Gene Abbr	Nfkb2
Species	Rat
Size	10 ug
Vector	pCMV6Entry

Target Gene

NFKB2

Background

This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]

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