Panoply™ Human NFKB2 Knockdown Stable Cell Line

Name: Panoply™ Human NFKB2 Knockdown Stable Cell Line
SKU: CSC-DC010342
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC010342

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC010342
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	NFKB2
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) [ Homo sapiens ]
Gene Symbol	NFKB2
Synonyms	p52; p105; H2TF1; LYT10; LYT-10; NF-kB2
Gene ID	4791
Uni Prot ID	Q00653
m RNA Refseq	NM_001077494.2
Protein Refseq	NP_001070962.1
Chromosome Location	10q24
Function	DNA binding; protein binding; sequence-specific DNA binding transcription factor activity; transcription coactivator activity;
Pathway	Activated TLR4 signalling, organism-specific biosystem; Alternative NF-kappaB pathway, organism-specific biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; Cytosolic sensors of pathogen-associated DNA, organism-specific biosystem; DAI mediated induction of type I IFNs, organism-specific biosystem; EBV LMP1 signaling, organism-specific biosystem; Epstein-Barr virus infection, organism-specific biosystem;
MIM	164012

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